GC-LC CONCORDANCE software by SPECTROCHROM automates chromatograms comparisons between complex products (up to 1000 compounds in a mixture), by simultaneously correcting time shifts, and random fluctuations of retention times (RT) or retention index (RI) (Kovats) of these components due to column degradation.

chromatogramme CPG produit pétrolier 515 pics
Chromatogram in CPG of a petroleum product (515 peaks)

Unique Software for Automatic Chromatograms comparison

GC-LC CONCORDANCE is a unique software, mixing theories of deductive mathematics of polynomials functions (P=AnX^n with n=30) and algorithms of the neurological networks (recognition and adaptability).

chromatogrammes hplc extraits protéiques protéome cellulaire

Chromatograms in HPLC of protein extracts of the cellullar proteomics.

Typical applications are control of raw materials and finished products in the perfume industry, but also to oils, petrol residues, proteomic and pollution. More generally, it concerns chemistry products controlled by GC and HPLC chromatography techniques.

Indeed, phase ageing of the column varies in non linear and random ways depending on injected products and their concentration.

Reasons of these variations in GC or LC:

  • Injection mode
  • Gas control
  • Temperature control
  • Chemistry of the Injected product
  • Reconditioning of the Gas chromatograph
  • Sample impurities
  • Phase oxidation (O2 in carrier gas)
  • Quality of pumps in HPLC

Upon repeating analysis, retention time differences of components will vary from seconds to minutes. Moreover if the analyzed product has hundreds of components separated by a few seconds on the chromatogram, the manual identification is long, difficult and is prone to human error.

Today even if a gas chromatograph has all the new electronic regulation developments of temperature and gas flow rates, it is unable to balance these complex variations.

An automatic and accurate analysis is now possible with GC-LC CONCORDANCE!