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Improve Drastically your Productivity

Improve Drastically your Quality Control

The control is precise, reliable and it is no longer subject to errors of comparison due to visual monitoring.

Example: Below the control of a perfumed solution compared to a reference, the zone is strongly expanded in X and Y coordinates and a retention time shifting of several minutes of the peaks does not allow to superimpose the two chromatograms.

It’s very difficult, almost impossible, for a chemist to detect that Coumarin in the reference has been replaced by allyl cyclohexyl propionate in the sample. The retention time difference of the peaks (~2 minutes in this zone) is due to environmental changes of the chromatograph (ageing of the column, gas.)


Zoom of the chromatograms “Sample/Reference” which presents an anomaly

advantage compounds error detection
chromatograms zoom comparison

GC-LC CONCORDANCE will compensate these retention time shiftings and will detect instantaneously that the Coumarin is not in the sample and that another unknown product is there compared to the reference.

simple report of chromatograms comparisons

You can notice that the software reveals that three other products, present in the sample, do not correspond in concentration to the peaks of the reference (thresholds fixed by the chemist).

Equation and curve for non-linear RT shifting

The polynomial equation calculated for the correction of peak shiftings between the two chromatograms is of order 3

Y = A0 + A1X ^ 1 + a2x ^ 2 + A3X ^ 3

It will be used to solve initial adjustment before applying random and subtle changes linked to complex variations in chromatography (repeatability of the chromatograph temperature, chemical modification of the phase in the column)